For decades, residents of Chicago's Cabrini-Green have heard stories of a supernatural killer known only as Candyman, allegedly the resurrected soul of a murdered slave wanting to exact vengeance on his killers. In the present day, visual artist Anthony McCoy (Yahya Abdul-Mateen II) and his girlfriend (Teyonah Parris) have moved into a luxury loft condo in a now gentrified Cabrini-Green. A chance encounter with a local old-timer (Colman Domingo) exposes Anthony to the true story behind Candyman and unleashes a wave of violence that puts him on a collision course with destiny.